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Extra resources for Hidden Treasure: The National Library of Medicine (Sappol, Hidden Treasure)
President of the nationwide Dental organization, and his autographed hand silhouette. Dr. Thorpe used to be Whitslar’s buddy and recipient of the reward album. Dental Hand Silhouette present Album contrary: photo of Edward C. Kirk [Church? ] and autographed hand silhouette. Scenes from Japan: a sufferer present process dental therapy and other people having a meal, with autographed hand silhouette of eastern dentist [Seimori? ] Shimura. picture of “ ‘Zim’ the artist” (Eugene Zimmerman, above, clockwise from most sensible left: a political cartoonist and caricaturist for Puck and decide, the main well known late-nineteenth-, early-twentieth-century American satirical weeklies), with autographed hand silhouette. Zim is the one nondentist featured within the present album. Above his picture, a quote: “When drawing distorted beneficial properties, you'll notice that your personal face assumes comparable contortions” (from Zim, This and That approximately cartoon [New York, 1905], p. 25). Palmistry diagram; unidentified resource. Dental Hand Silhouette reward Album hello d d e n tr e a sur e 151 Molecular biology in the back of the blackboard Marshall W. Nirenberg Papers (1937 – 2003) Marshall W. Nirenberg nationwide Library of drugs, Profiles in technology: http://profiles. nlm. nih. gov/JJ/. Manuscript papers; 159 packing containers and oversize fabrics; 721⁄2 linear toes; photo courtesy of Nature © 2011 T he picture is dramatic, extra dramatic in its personal means than the well-known one in every of James Watson and Francis Crick. Like that picture, this one portrays younger scientists within the throes — the joys — of collaboration. The names are usually not in addition identified: the younger males are Marshall Nirenberg (1927 – 2010) and Heinrich Matthaei (b. 1929). yet their accomplishment used to be simply as vital. Watson and Crick labored on molecular reproduction — the DNA molecule shaped of 2 entwined strands, every one strand keeping the knowledge that courses life’s unfolding, every one strand an important as cells divide. Nirenberg and Matthaei labored on molecular functionality. For the constitution of DNA lent itself to considering a “code. ” With a trend of nucleic acid base pairs, A, T, G, and C, laid out to shape a strand of DNA, a key used to be had to offer meaning — just as Morse code interprets dots and dashes into letters and phrases. hence the dots and dashes have been nucleic acid bases, the letters have been amino acids, and the phrases have been proteins, the advanced molecules that consultant mobile activities similar to “break down a sugar,” or “create a mobile wall,” or maybe “make a brand new molecule of DNA. ” Nirenberg and Matthaei cracked that code. Their technique used to be simplicity itself (which didn’t make it easy). Make a man-made nucleic acid, run it via a ribosome (which assembles proteins), and notice what comes out. First, installed a strand of all U’s (uracil, a stand-in for T, during this case). Out comes an artificial molecule made exclusively of the amino acid phenylalanine, a number of copies joined head-to-tail like a protein. So UUU (the code was once shaped of 3 bases) potential phenylalanine. fluctuate the quantities of the nucleic acid bases and notice what amino acids meet up and in what proportions.